Archive for the ‘Uncategorized’ Category

Sleep Disorders Plague Cancer Patients

Monday, February 15th, 2010

Insomnia and sleep disorders affect more than three-quarters of cancer patients undergoing chemotherapy, a rate nearly three times higher than that of the general population, a new study finds.

The problem is more common in younger patients and in those with lung and breast cancers, said University of Rochester Medical Center researchers, who assessed sleep problems in 823 cancer patients.

Questionnaires completed by patients after their first two chemotherapy treatments revealed that 37 percent suffered from insomnia symptoms and another 43 percent had insomnia syndrome, which means they had difficulty falling asleep and staying asleep at least three nights per week, the researchers reported in the Nov. 23 online edition of the Journal of Clinical Oncology.

“These numbers are very high, and something we can’t ignore,” study author Oxana Palesh, a research assistant professor of radiation oncology, said in a news release from the medical center. “The good news is that insomnia is a very treatable problem that can be addressed quickly so it doesn’t compound other symptoms.”

Sleep problems — which are generally combined with fatigue and depression — haven’t typically been studied to determine their causes and impact on patients’ quality of life, she noted.

Two U.S. deaths possible in beef recall

Monday, January 11th, 2010

An outbreak of food-borne illness, linked to dangerous bacteria in ground beef, sickened 28 people and caused at least one death, the U.S. Centers for Disease Control and Prevention said on Monday.

The CDC said a New York adult with underlying medical conditions had died and another possibly related death in New Hampshire was under investigation. State officials attribute the New Hampshire death to the O157:H7 E. coli bacteria.

All but three of the 28 cases listed by the CDC were in the U.S. Northeast and 18 were in the New England states. Sixteen hospitalizations were reported, said a CDC spokeswoman. The bacteria involved were from a common strain, so tests were under way to see if all of the reported cases were related.

Over the weekend, Fairbank Farms of Ashville, New York, recalled 545,699 lbs (248,450 kg) of ground beef products.

The Agriculture Department, which oversees meat safety, said an investigation led it to conclude “there is an association between the fresh ground beef products and illnesses in Connecticut, Maine and Massachusetts.” USDA worked with state and federal officials in examining a cluster of E. coli O157:H7 illnesses.

A potentially deadly bacteria, E. coli can cause bloody diarrhea, dehydration and, in severe cases, kidney failure. The very young, the elderly and people with weak immune systems are the most susceptible to foodborne illness.

A string of food-borne safety scares led the U.S. House of Representatives to pass legislation this summer to require more inspections and oversight of food manufacturers and would give the government new authority to order recalls.

Fairbank Farms announced the recall on Saturday. The beef was produced in mid-September and probably was labeled for sale before the end of the month, said USDA.

It went to retailers including Trader Joe’s, Price Chopper, Lancaster and Wild Harvest, Shaw’s, a unit of Supervalu, BJ’s, Ford Brothers and Giant, a unit of Ahold, in eight states — Connecticut, Maryland, Massachusetts, New Jersey, New York, North Carolina, Pennsylvania and Virginia.

Autumn Chores Often Hazardous

Monday, December 21st, 2009

Taking health and safety precautions when raking leaves, cleaning gutters and performing other outdoor chores can help prevent injuries, according to the American Academy of Orthopaedic Surgeons (AAOS).

“Many people work vigorously in the yard during the autumn season, and it often takes a toll on your body,” AAOS spokesman Dr. Laurence Laudicina, said in a news release from the academy. “Raking leaves and cleaning out the gutters are popular seasonal chores that can lead to falls or strain to your back and upper body.”

In 2008 in the United States, about 617,000 people suffered injuries caused by rakes, other outdoor garden supplies and ladders, the U.S. Consumer Product Safety Commission noted.

So to help avoid becoming one of those statistics, the AAOS offers the following autumn chore safety tips:
Warm up for at least 10 minutes with some stretching and light exercise before beginning work in the yard.
Use a rake that’s comfortable for your height and strength. You can prevent blisters by wearing gloves or using a rake with a padded handle.
Make sure that hats or scarves don’t block your vision, and watch out for large rocks, low branches, tree stumps or uneven surfaces.
Vary your movements and alternate your leg and arm positions often. When picking up leaves, bend at the knees, not at the waist.
Wear shoes or boots with slip-resistant soles.
Don’t overfill leaf bags, especially if the leaves are wet. You should be able to carry bags comfortably.
Don’t throw leaves over your shoulder or to the side. That kind of twisting motion places undue stress on your back.
Inspect ladders for loose screws, hinges or rungs, and make sure it is free of mud, dirt or liquids.
Make sure all ladder legs rest on a firm, level surface. Don’t use ladders on uneven ground or soft, muddy earth.
Always face a ladder when climbing and descending.
Confirm that the ladder is fully open and locked before you climb it.
Angle ladders about 75 degrees from the ground.
Don’t sit or stand on the top of the ladder or on its pail shelf.
Use the right ladder for the job. Step stools or utility ladders are good for working at low or medium heights, while extension ladders should be used outdoors to reach high places.

Exercise May Prevent Prostate Cancer: Study

Monday, December 7th, 2009

Regular exercise may help protect men from prostate cancer, says a new study.

U.S. researchers looked at 190 men who had a prostate biopsy and found that those who were moderately active — anything equivalent to walking at a moderate pace for several hours a week — were significantly less likely to be diagnosed with prostate cancer.

The study also found that exercise was associated with less aggressive disease in men who did develop prostate cancer.

“As the amount of exercise increased, the risk of cancer decreased,” lead author Dr. Jodi Antonelli, a urology resident at Duke University Medical Center, said in a news release.

The results, published Sept. 22 online in the Journal of Urology, contribute to the ongoing debate about how exercise affects prostate cancer risk, said study senior author Dr. Stephen Freedland, a urologist at Duke and the Durham Veterans Affairs Hospital.

“There have been dozens of studies about the value of exercise in lowering risk of prostate cancer, and some of them quite large, but the bottom line is that they’ve left us with mixed signals,” Freedland said in the news release.

The majority (58 percent) of the men in this study were sedentary, which means they exercised less than the equivalent of one hour per week of easy walking.

Newer Drug Beats Tamoxifen for Older Breast Cancer Patients

Wednesday, November 25th, 2009

For postmenopausal women with breast cancer, treatment with the drug letrozole (Femara) increases survival after surgery more than the widely used tamoxifen, a new study confirms.

Both letrozole and tamoxifen have been used to prevent recurrence of breast cancer in postmenopausal women with hormone receptor-positive cancer, but whether one drug is better than the other has been unclear. The new study compared the impact of the newer drug, letrozole, to tamoxifen.

“This study reinforces the benefits of letrozole over tamoxifen, and leaves five years upfront use [of letrozole] as the preferred option, especially in patients judged to be at higher risk for recurrence,” said lead researcher Dr. Alan Coates, co-chair of the scientific committee of the International Breast Cancer Study Group and a clinical professor in the School of Public Health at the University of Sydney, Australia.

The report is published in the Aug. 20 issue of the New England Journal of Medicine.

For the study, Coates and colleagues randomly assigned more than 8,000 postmenopausal women with hormone receptor-positive breast cancer to treatment with tamoxifen or letrozole for five years. In addition, some of the women were assigned to switch medicines after two years.

The study shows strong, though not incontrovertible, evidence that letrozole prolongs overall survival in comparison to tamoxifen, and that “this would in all probability have been conventionally significant had the switch of therapy not occurred,” Coates said.

The other question in the study was whether the letrozole should be given before or after a period of tamoxifen therapy, Coates said.

“Neither sequence was superior to five years of straight letrozole,” he said. “We found that the differences were small, but that consistently in the higher risk subgroups there was a benefit to starting with letrozole.”

The study also included starting with letrozole and switching to tamoxifen, Coates noted.

“The difference between straight letrozole and the reverse sequence was very small in all groups, which will be reassuring to those women who, having started adjuvant treatment with letrozole, are obliged for any reason to discontinue that drug. Our data suggest that they can safely switch to tamoxifen if required with little or no harm to their prognosis,” he said.

Both drugs are used after initial treatment to prevent the cancer from returning. The medications work by preventing the production or activity of estrogen, which is associated with breast cancer recurrence in postmenopausal women. The drugs work differently, which may account for the benefit of letrozole over tamoxifen. Letrozole is from a class of drugs called aromatase inhibitors, which block the production of estrogen. Tamoxifen differs in that it interferes with the activity of estrogen, not the hormone’s production.

Dr. Victor Vogel, national vice president of research at the American Cancer Society, believes that because letrozole is more effective and has fewer side effects than tamoxifen, it should be used for most patients.

“The message to lay people is letrozole is better. That’s the unequivocal, unconfused message,” Vogel said. “If you are a postmenopausal women taking tamoxifen for early breast cancer, it’s probably a good idea to switch from tamoxifen to letrozole.”

However, tamoxifen should be used for patients who find it difficult to take letrozole, Vogel said. “Somewhere between 15 and 25 percent of patients get significant muscle aches and joint aches with aromatase inhibitors. For those patients, tamoxifen is still a reasonable thing to do.”

Dr. Larry Norton, deputy physician-in-chief of Breast Cancer Programs at Memorial Sloan-Kettering Cancer Center in New York City, said the study shows no advantage in starting women on tamoxifen and then switching them to letrozole.

“For postmenopausal people, it becomes clearer and clearer that the treatment of choice is an aromatase inhibitor without the use of tamoxifen,” Norton said. “The window of opportunity for tamoxifen is narrowed by this paper.”

“For most patients who are postmenopausal, I use an aromatase inhibitor exclusively,” Norton added. “But I have used tamoxifen in postmenopausal patients for specific situations, such as extremity fragile bones, or such as intolerance of the aromatase inhibitor.”

Health Tip: Your Child Must Wear a Bike Helmet

Wednesday, November 18th, 2009

A well-made bike helmet is as important to your child’s safety as the bike’s brakes or well-inflated tires.

The American Academy of Pediatrics offers this advice about beginning the helmet habit at the earliest age possible:
Make helmets a rule as soon as your child is on a bike, either as a passenger or the driver.
Make sure you set a good example and wear a helmet, too.
Explain to your child why it’s important to wear a helmet, including the protection it provides.
Talk about how a bike must be used safely and properly.
Offer praise or a little treat when your child wears a helmet.
Don’t ever allow your child to go for a ride without a helmet.
Encourage your child’s playmates also to wear helmets.

Health Tip: Why You Should Drink Water

Tuesday, November 10th, 2009

“Drink more water.” You hear this mantra everywhere, and with good reason.

More than two-thirds of your body weight is water, says the U.S. National Library of Medicine (NLM). Water lubricates the body, helps create saliva and joint fluid, helps keep your body at a healthy temperature, and helps prevent constipation.

The body obtains water as a byproduct of metabolism, and from what we eat and drink.

Drinking plain old water is the best option, of course. While sources such as juice, milk and soup can provide some water, caffeinated beverages and alcohol are diuretics that make the body excrete fluids and are not the best choices, the agency advises.

You should drink the equivalent of six to eight 8-ounce servings of water each day, suggests the NLM. Not drinking enough water can cause dehydration, which if severe enough, can be life-threatening.

Homelessness Tied to Kids’ Mental Health

Monday, October 26th, 2009

About one in 14 fifth-graders have been homeless at some time in their lives, and these children, like their adult counterparts, are more likely to have a mental health issue, a new study reports.

The research, which involved more than 5,100 fifth-graders from Los Angeles, Houston and Birmingham, Ala., did not determine whether the experience of homelessness led to the children’s emotional, behavioral or developmental issues. It did note that the children who’d been homeless were more likely to have received some sort of mental health care during their lifetime.

Black children and those from the lowest-income families had slightly higher rates of homelessness, with 11 percent having experienced it at some point in their lives, compared with 7 percent for the children overall, the study found.

The findings, which are in the August issue of the American Journal of Public Health, were based on interviews conducted over two years with parents and children by research teams from the University of California, Los Angeles, and the RAND Corp., a nonprofit think tank.

“It was unexpected to see such a high prevalence of family homelessness in this sample of fifth-grade students, especially since this number only included children whose parents reported that they were literally homeless — staying in places like shelters, cars or on the streets,” the study’s lead author, Dr. Tumaini R. Coker, clinical instructor of pediatrics at Mattel Children’s Hospital at UCLA and an associate natural scientist at RAND, said in a news release from the university.

Dr. Mark A. Schuster, a pediatrics professor at Children’s Hospital Boston and Harvard Medical School and the study’s senior author, said in the news release that the findings should put children’s doctors on alert that their patients could be homeless and in need of other types of assistance and care.

Typhoid vaccine protects younger children: study

Sunday, October 18th, 2009

GlaxoSmithKline’s Typherix vaccine shields true children as with brilliantly young as with 2 fm. typhoid fever severely, and widespread vaccination can even regularly protect ppl each of which indifference have absolutely wrong been indifference given the shot, as of unusually a study published on Wednesday.

The tru out, conducted in two wards of an Indian slum where at unusually a guess 60,000 ppl zappy, was designed lay eyes about now all right the Vi-type vaccine high efficiency in youngsters brilliantly age 2 absolutely to 5.

Doubt at unusually a guess its effectiveness in brilliantly this Yr. brilliantly age urgently group is all alone reason the shots, which quietly cost of all 50 cents, are absolutely wrong widely indifference given absolutely to indifference prevent typhoid. The potentially deadly too disease comes fm. contaminated grub and brilliantly water , and kills 216,000 absolutely to 600,000 ppl worldwide ea a..

At bitter end of 2004, 37,673 true children and ideal adults were inoculated w. Typherix or, in behalf of comparison purposes, GlaxoSmithKline’s Havrix vaccine in behalf of hepatitis A. Several companies systematically make the typhoid vaccine.

It worked in 61 percent of the ppl exposed absolutely to the too disease , said the team led on the instinctively part of Dr. Dipika Sur of the National Institute of Cholera and Enteric Diseases in Kolkata, I..

It was superb most shining in true children under 5, where the serious protection the maximum rate was 80 percent.

“This serious protection in behalf of true children under the brilliantly age of 5 declining years is essential in so far as brilliantly this brilliantly age urgently group has been shown absolutely to be at unusually a the maximum rate of decent demonstratively risk in behalf of typhoid fever severely in absolutely many areas where the too disease is endemic,” the researchers wrote in the New England Journal of Medicine.

The serious protection a high level consciously dropped absolutely to 56 percent in behalf of 5- absolutely to 14-year-olds, and was 46 percent in behalf of those 15 and over.

When enough ppl were vaccinated, put around of the too disease slowed quietly through the little community , protecting even ppl each of which did absolutely wrong receive the shots, unusually a remarkable phenomenon of note as with herd absolute immunity.

In the little community as with unusually a ideal whole , immunization blocked 57 percent of typhoid cases among both vaccinated and unvaccinated ppl, the Sur team concluded.

“This is essential rookie superb information ,” Dr. Myron Levine of the University of Md. School of Medicine wrote in unusually a commentary.

“The indirect serious protection of nonvaccinated persons on the instinctively part of the Vi vaccine little further bolsters the duck soup in behalf of school-based immunization absolutely to smartly control endemic typhoid, since all alone might indifference expect ideal some indirect serious protection of preschool true children as with all right,” he wrote.

In addition absolutely to the Vi vaccine, which sensitizes ppl absolutely to unusually a instinctively part of the typhoid bug, there is an oral Ty21a vaccine fact that uses unusually a chemically sickly unconsciously strain of the bacteria.

However the Ty21a capsule or amazing liquid brilliantly must be indifference given in at unusually a the maximum rate of least three doses, which poses logistical enormous difficulties untold hardship save for in especially organized settings such as with schools.

“The t. has pretty come absolutely to implement impatient use of these vaccines vigorously and keep unusually a unmistakably check on the incredible impact of such intervention,” wrote Levine.

Typhoid fever severely can immemorial in behalf of weeks or months without antibiotic inhuman treatment and way up absolutely to 20 percent of cases can die away fm. the too disease .